Synchronization settings are saved in the Session. There are a lot of these, some apply to each track, and a few are "global" and are configured under the Globals->Transport section. Mobius doesn't really care about time signature unless you are making it generate MIDI clocks where it influences the tempo calculation.
It can also effect recording synchronization, when determining where bars are. Usually it gets the beats per bar directly from the host and there is no need to set it. Some hosts may not pass this to the plugin, and occasionally it is useful to override whatever the host says. To do that go to the session Globals->Sync->Host and check the "Override host beats per bar" and then enter a number.
How quantization is saved is a bit complicated. If you're using common quantization, this is in Session->Quantuze. If you are using function specific quantization where every function can have a different quantize value, this is not saved in the session, it is global. If that's what you're using I'll describe that in more detail.